Invited Speakers
Glenn Tan Wei Leong
Current Position
Head, Department of General SurgeryHead of Service, Vascular and Endovascular Surgery
Tan Tock Seng Hospital, Singapore
Peripheral Artery SessionFriday, Oct. 21, 2022 08:30-10:06 @Ballroom I

Topic: Acute aortic thrombosis presenting as acute limb ischemia in two young, non-atherosclerotic patients


Mobile aortic thrombus (MAT) in a normal aorta is a rare entity with majority (up to 82.4 per cent) of cases diagnosed only after an arterial embolic event. Cardiac sources or proximal aortic disease account for 90 per cent of peripheral arterial embolic events and it is rare for the non-aneurysmal aorta to contribute to these embolic events. A normal cardiac evaluation coupled with lack of smoking history and atherosclerotic risk factors, should trigger further evaluation for Mobile Aortic Thrombus and pro-thrombotic causes in young patients. In this current pandemic, we have also increasingly recognise COVID-19 infection as a cause for mobile aortic thrombus. We describe our experience in treating acute lower limb ischaemia secondary to mobile aortic thrombus.





• MB ChB, University of Glasgow, Medical School – 2003
• Intercollegiate MRCS, Royal College of Physicians and Surgeons of Glasgow – 2005
• Master of Medicine (Surgery), National University of Singapore – 2007
• Joint Specialty Fellowship Exit Examination in General Surgery / FRCSEd (Gen) with the award of the College of Surgeons, Singapore, Gold Medal – 2010

Research Experience

・Co-Investigator, Singapore INfra-Genicular Angioplasty with PAclitaxel-eluting balloon for Critical Limb Ischaemia (SINGA-PACLI) Trial
・Co-Investigator, BIOLUX PIII Registry
・Clinical Principal Investigator, SingHealth Foundation – National Health Innovation Centre Joint MedTech Grant 2015 ($100,000)
・Clinical Principal Investigator, Medtech Innovation Grant (MIG) 2016 from A*STAR Biomedical Research Council


・College of Surgeons, Singapore Gold Medal (2010)
・National Healthcare Group (NHG) Education Leaders Award (2016)
・National Healthcare Group Young Achiever Award (2016)

Selected Publications
  • Management of blunt traumatic thoracic aorta injuries with endovascular stent grafts in a tertiary hospital in an Urban Asian City Glenn WL Tan, C H Pek, D Wong, S Punamiya, M T Chiu, V Appasamy, K H Chia, C W Lee Annals of Vascular Surgery 2011;25(5):605-611(PMID: 21435831) 
  • Aortoenteric Fistula Treated with Endovascular Aortic Stent-Graft and Bilateral Chimney Stent-Grafts to Renal Glenn WL Tan, D Wong, S Punamiya, B P Tan, C Vu, B Ang, D Foo, K H Chia Annals of Vascular Surgery 2012;26:422.e13-422.e16 (PMID: 22284779)
  • Early Experience and Lessons Learnt with Customized Fenestrated Thoracic Endovascular Aortic Reconstruction for Aortic Arch Pathology in Asian Population Tan GWL, Quek L, Tan BP, Pua U Cardiovasc Intervent Radiol 2017 Dec 13 (PMID: 29238868) ・Use of Multilayer Stent and Fenestrated Endograft in a Single Session to Treat Long-Segment Aorta Pua U, Tan GWL, Kolvenbach, Quek LHH Ann Vasc Surg 2019 Aug 5 (PMID: 31394240)
  • Endovascular Repair of Concomitant Aortic Arch and Kommerell Aneurysms after failed surgical debranching Ong DY, Quek LHH, Tan GWL, Pua U J Vasc Interv Radiol 2021 Nov 9:S1051-0443(21)01468-8 (PMID: 34763087)
  • Endovascular repair of mycotic aortic aneurysm confers good medium-term outcomes and aneurysmal sac resolution Lim YT, Tay WM, Lo ZJ, Pua U, Quek LHH, Tan BP, Chandrasekar S, Tan GWL Singapore Med J 2020 Dec 2 (PMID: 33264562)

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